Indianapolis Colts vs. Arizona Cardinals – NFL Week 16 (12/25/21) | Kickoff
The second game on the NFL schedule on the holiday features a pair of teams coming off differing results, but are still in the thick of their respective conference’s playoff pictures, as the Arizona Cardinals look to rebound when they host the Indianapolis Colts.
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The Cardinals are coming off an embarrassing loss to the Detroit Lions last week. Despite outgaining Detroit 398-338, Arizona was only able to find the endzone once. They have now lost back-to-back games for the first time this season, but are still in the lead in the NFC West with a 10-4 record. A win on Saturday will all but secure a playoff spot for the Cardinals.